CED-ähnliche Erkrankungen

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CED-ähnliche Erkrankungen sind Krankheitsbilder, die Symptome und/oder Entzündungsprozesse aufweisen, die denen von Chronisch Entzündlichen Darmerkrankungen (CED) wie Morbus Crohn oder Colitis ulcerosa ähneln, jedoch andere Ursachen oder eine abweichende Pathophysiologie haben. In diesem Kapitel nennen wir einige Beispiele für Erkrankungen des Verdauungstraktes, die einer CED ähneln.

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Infektiöse Darmerkrankungen

Ursache: Bakterien (z. B. Clostridioides difficile, Salmonella, Campylobacter), Viren oder Parasiten (z. B. Giardia lamblia).

Symptome: Akuter Durchfall, Bauchschmerzen, Fieber, Übelkeit.

Besonderheit: Treten plötzlich auf und heilen meist nach Behandlung aus.

Mikroskopische Colitis

Formen: Kollagene und lymphozytäre Kolitis.

Symptome: Chronischer, wässriger Durchfall, Bauchschmerzen, Gewichtsverlust, Müdigkeit.

Besonderheit: Entzündung nur mikroskopisch nachweisbar; häufig bei älteren Frauen.

Zöliakie (Glutenunverträglichkeit)

Ursache: Autoimmune Reaktion auf Gluten.

Symptome: Durchfall, Bauchschmerzen, Blähungen, Müdigkeit, Gewichtsverlust.

Besonderheit: Schädigung der Dünndarmschleimhaut; Besserung durch glutenfreie Ernährung.

Reizdarmsyndrom (RDS)

Ursache: Funktionelle Störung ohne organische Ursache.

Symptome: Bauchschmerzen, Blähungen, Durchfall oder Verstopfung, Übelkeit.

Besonderheit: Chronischer Verlauf; keine Entzündung nachweisbar.

Divertikulitis

Ursache: Entzündung von Ausstülpungen der Darmwand (Divertikel).

Symptome: Schmerzen im linken Unterbauch, Fieber, Übelkeit, Durchfall oder Verstopfung.

Besonderheit: Akuter Verlauf; häufig bei älteren Menschen.

Eosinophile Gastroenteritis

Ursache: Ansammlung von eosinophilen Immunzellen im Verdauungstrakt, oft allergisch bedingt.

Symptome: Bauchschmerzen, Durchfall, Übelkeit, Gewichtsverlust.

Besonderheit: Seltene Erkrankung; betrifft häufig den gesamten Magen-Darm-Trakt.

Ischämische Kolitis

Ursache: Eingeschränkte Blutversorgung des Darms, z. B. durch Gefäßverengung oder Thrombosen.

Symptome: Plötzliche Bauchschmerzen, blutiger Stuhl, Übelkeit.

Besonderheit: Meist bei älteren Menschen; akuter Verlauf.

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Quellenangabe

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Fazit

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CED-ähnliche Erkrankungen können ähnliche Symptome wie Morbus Crohn und Colitis ulcerosa zeigen (z. B. Durchfall, Bauchschmerzen, Blut im Stuhl), haben jedoch oft andere Ursachen oder Mechanismen. Eine exakte Diagnose durch Anamnese, Endoskopie, Bildgebung und Biopsien ist entscheidend, um die richtige Therapie einzuleiten.

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Eosinophile Ösophagitis (EoE)

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Die eosinophile Ösophagitis (EoE) ist eine chronische Entzündung der Speiseröhre, meist durch eine allergieähnliche Reaktion. Typisch sind Schluckbeschwerden und das Gefühl, dass Nahrung stecken bleibt.

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Stuhldringlichkeit bei CED

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Stuhldringlichkeit: Ein plötzlicher, sehr starker Stuhldrang, der den sofortigen Gang zur Toilette notwendig macht, kann für viele Betroffene von Chronisch Entzündlichen Darmerkrankungen (CED) besonders belastend sein.

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Beschwerden außerhalb des Darms

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Neben dem Verdauungstrakt, können im Zuge einer Chronisch Entzündlichen Darmerkrankung (CED) auch in anderen Organen Komplikationen entstehen. Augen, Haut, Gelenke uvm. können betroffen sein.